BRAIN A JOURNAL OF NEUROLOGY Alzheimer’s disease pattern of brain atrophy predicts cognitive decline in Parkinson’s disease
نویسندگان
چکیده
1 Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104-3339, USA 2 Parkinson’s Disease Research, Education and Clinical Centre (PADRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, USA 3 Mental Illness Research, Education and Clinical Centre (MIRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, USA 4 Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104-3339, USA 5 Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104-3339, USA 6 Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104-3339, USA 7 Avid Radiopharmaceuticals, Philadelphia, PA 19104, USA
منابع مشابه
Alzheimer's disease pattern of brain atrophy predicts cognitive decline in Parkinson's disease.
Research suggests overlap in brain regions undergoing neurodegeneration in Parkinson's and Alzheimer's disease. To assess the clinical significance of this, we applied a validated Alzheimer's disease-spatial pattern of brain atrophy to patients with Parkinson's disease with a range of cognitive abilities to determine its association with cognitive performance and decline. At baseline, 84 subjec...
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